色谱

色谱

• 专论与综述 • 上一篇    下一篇

多维液相色谱分离技术及其在蛋白质组研究中的应用

朱贵杰, 梁振, 张丽华*, 张玉奎   

  1. National Chromatographic R. &A. Center, CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, the Chinese Academy of Sciences, Dalian 116023, China
  • 收稿日期:2009-08-04 修回日期:2009-09-02 出版日期:2009-09-30 发布日期:1982-03-25
  • 通讯作者: 张丽华

Developments and applications of multidimensional liquid chromatography in proteomics

ZHU Guijie, LIANG Zhen, ZHANG Lihua*, ZHANG Yukui   

  1. National Chromatographic R. &A. Center, CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, the Chinese Academy of Sciences, Dalian 116023, China
  • Received:2009-08-04 Revised:2009-09-02 Online:2009-09-30 Published:1982-03-25
  • Contact: ZHANG Lihua

PDF

950

被引次数

18

摘要： 对近年来多维液相色谱技术及其在蛋白质组学研究中的应用进行了系统综述。详细描述了由不同液相色谱模式构建的多维液相色谱系统,并介绍了其在蛋白质组表达谱、翻译后修饰、定量等方面的应用。此外,还对多维液相色谱的发展趋势和前景进行了展望。

关键词: 蛋白质组学, 多维液相色谱技术, 综述

Abstract: This review summarizes the recent developments of multidimensional liquid chromatography (MDLC) techniques, and their applications in proteomics study, including expression profiling, post-translational modification, quantitative analysis, and so forth. In addition, the prospect and further developments of MDLC are discussed.

Key words: proteomics, review , multidimensional liquid chromatography