烟碱样品前处理及分析方法研究进展

doi:10.3724/SP.J.1123.2018.07006

摘要/Abstract

摘要：

烟碱是评价烟草及其制品的感官品质及内在质量的重要指标，同时也是监测食品、环境及人体中尼古丁暴露程度的关键因素。烟碱所在基质复杂，样品多样，针对不同检测环境及要求选择合适高效的分析方法对成功测定烟碱含量至关重要。该文介绍了测定烟草及生物样品中烟碱含量的样品前处理技术（固相/液相微萃取技术和分子印迹法）和常用的检测方法（分光光度法、液相色谱法、气相色谱法、毛细管电泳法、电化学法），评述了每种方法的适用范围、应用实例和研究进展，并讨论了各种检测方法的灵敏度、准确性和检测效率等。

关键词: 检测方法, 前处理, 烟碱, 综述

Abstract:

Nicotine is an important indicator in the quality evaluation of tobacco and its related products. Moreover, it is essential to monitor nicotine presence in the environment, food, and human organs. Therefore, the development of a suitable and efficient determination method is crucial to precisely detect nicotine in various samples and complicated matrices. This article reviews the methods of sample preparation (molecular imprinting technology and solid phase/liquid phase microextraction) and methods for nicotine analysis, such as spectrophotometry, liquid chromatography, gas chromatography, capillary electrophoresis, and electrochemical methods, reported in recent years. The advancement in the applications and scopes of these methods are discussed. Furthermore, the sensitivity, accuracy, and detection efficiency of these methods are elaborated on the basis of the reported nicotine determination methods.

Key words: detection methods, nicotine, pretreatment, review

中图分类号:

O658

张佳杰, 孟子晖, 薛敏, 魏天晔. 烟碱样品前处理及分析方法研究进展[J]. 色谱, 2018, 36(11): 1081-1087.

ZHANG Jiajie, MENG Zihui, XUE Min, WEI Tianye. Advances in nicotine pretreatment and determination method[J]. Chinese Journal of Chromatography, 2018, 36(11): 1081-1087.

参考文献

[1] De Bardeleben M Z. Dictionary of Tobacco Terminology. 2nd ed. New York:Philip Morris, 1987:4
[2] Yang J L, Zhou J B. Acta Physico-Chimica Sinica, 2013, 29(2):377 杨继亮, 周建斌. 物理化学学报, 2013, 29(2):377
[3] Ogg C L, Willits C O, Ricciuti C. Anal Chem, 1950, 22(2):335
[4] Markwood L N, Markunas P C. J AOAC Int, 1939, 22(2):427
[5] Farsalinos K. Ther Adv Respir Dis, 2018, 12(1):1
[6] Lim H H, Shin H S. Anal Bioanal Chem, 2017, 409(5):1247
[7] March J G, Cerdà V. Talanta, 2016, 156/157:204
[8] Mahpishanian S, Sereshti H. Talanta, 2014, 130(5):71
[9] Boyaci E, Bojko B, Reyesgarcés N, et al. Sci Rep, 2018, 8(1):1167
[10] Ansari S, Karimi M. Talanta, 2016, 164:612
[11] Ashley J, Shahbazi M A, Kant K, et al. Biosens Bioelectron, 2017, 91:606
[12] Liu Y, Liu X L, Wang J. Anal Lett, 2003, 36(8):1631
[13] Lu C, Li H, Xu M, et al. Sep Sci Technol, 2015, 50(14):2124
[14] Franqui L S, Santos M G, Virtuoso L S, et al. Anal Methods, 2015, 7(21):9237
[15] Ceglowski M, Smoluch M, Reszke E, et al. Anal Bioanal Chem, 2017, 409(13):3393
[16] Xue M, Wang Y, Meng Z H, et al. J Liq Chromatogr R T, 2013, 36(19):2677
[17] Ma X Q, Meng Z H, Qiu L L, et al. J Chromatogr B, 2016, 1020:1
[18] Le Houezec J. Int J Tuberc Lung Dis, 2003, 7(9):811
[19] Wang Y, Xie T, Wang C, et al. Light Industry Science and Technology, 2015, 31(6):124 王奕, 谢涛, 王冲, 等. 轻工科技, 2015, 31(6):124
[20] Chen L J. Modern Agricultural Science and Technology, 2016(10):166 陈丽金. 现代农业科技, 2016(10):166
[21] Wu S X, Dong J Y. Tobacco Science & Technology, 2006(2):33 吴苏喜, 董君英. 烟草科技, 2006(2):33
[22] Huang F, Zhang Z, Wei X W, et al. Chinese Traditional Patent Medicine, 2015, 37(3):670 黄飞, 张哲, 魏先文, 等. 中成药, 2015, 37(3):670
[23] Zhu Z H, Zhang J X. Journal of Environment and Health, 1997(5):230 朱泽华, 张建霞. 环境与健康杂志, 1997(5):230
[24] Liu Y, Luo M B, Wu Z M. Jiangxi Chemical Industry, 2005(3):82 刘艳, 罗明标, 吴志猛. 江西化工, 2005(3):82
[25] Gao Y L. Journal of Luliang Higher College, 2006, 22(2):8 高玉莲. 吕梁学院学报, 2006, 22(2):8
[26] Chen Y W, Yin D L, Lian S X, et al. Journal of Natural Science of Hunan Normal University, 2005, 28(3):52 陈燕舞, 尹笃林, 廉世勋, 等. 湖南师范大学自然科学学报, 2005, 28(3):52
[27] Chu Z B, Zhou X G, Shui H F, et al. Journal of Agro-Environment Science, 2006, 25(Suppl):751 储志兵, 周新光, 水恒福, 等. 农业环境科学学报, 2006, 25(Suppl):751
[28] Xie X T, Zheng P, Zhu W M, et al. Chinese Journal of Analytical Chemistry, 2000, 28(9):1085 谢笑天, 郑萍, 朱伟明, 等. 分析化学, 2000, 28(9):1085
[29] Dong X C, Hou X, Yang G Y, et al. Journal of Yunnan University (Natural Sciences Edition), 2006, 28(6):518 董学畅, 侯霞, 杨光宇, 等. 云南大学学报:自然科学版, 2006, 28(6):518
[30] Ding C M, Lin S B. Journal of Environment and Health, 2008, 25(1):58 丁昌明, 林少彬. 环境与健康杂志, 2008, 25(1):58
[31] Hu H C, Meng C, Li F, et al. Journal of Fuzhou University (Natural Science), 2008, 36(2):308 胡海潮, 孟春, 李锋, 等. 福州大学学报(自然科学版), 2008, 36(2):308
[32] Tan F, Wang H M, Hu L, et al. Ningxia Journal of Agriculture and Forestry Science and Technology, 2012, 53(10):146 谭芳, 王海明, 胡丽, 等. 宁夏农林科技, 2012, 53(10):146
[33] Luo Q, Li Q. Modern Agricultural Sciences and Technology, 2018(8):242 罗琼, 李青. 现代农业科技, 2018(8):242
[34] Mccalley D V. J Chromatogr A, 2017, 1483:49
[35] Silva S I S, Bowdler P, Giltrow D, et al. Drug Test Anal, 2016, 8(7):676
[36] Wang H, Zhao Q, Song W, et al. Talanta, 2011, 85(1):743
[37] Siskos A P, Jain P, Römisch-Margl W, et al. Anal Chem, 2016, 89(1):656
[38] Earla R, Ande A, Mcarthur C, et al. Drug Metab Dispo, 2014, 42(2):282
[39] Tretzel L, Thomas A, Piper T, et al. J Pharm Biomed Anal, 2016, 123:132
[40] You G D, Rhee J, Park Y, et al. J Forensic Sci, 2016, 61(4):1149
[41] Abdallah I A, Hammell D C, Stinchcomb A L, et al. J Chromatogr B, 2016, 1020(5):67
[42] Li M X, Wang Q, Zhu J, et al. Chinese Journal of Chromatography, 2017, 35(8):826 李明昕, 王倩, 朱婧, 等. 色谱, 2017, 35(8):826
[43] Liachenko N, Boulamery A, Simon N. Fund Clin Pharmacol, 2015, 29(5):499
[44] Pérez-Ortuño R, Martínez-Sánchez J M, Fernández E, et al. Anal Bioanal Chem, 2015, 407(28):8463
[45] Marclay F, Saugy M. J Chromatogr A, 2010, 1217(48):7528
[46] Abu-Awwad A, Arafat T, Schmitz O J. Anal Bionanal Chem, 2016, 408(23):6473
[47] Lu W, Ferguson S G, Nichols D, et al. Anal Lett, 2015, 48(17):2715
[48] Kucharska M, Wesolowski W, Czerczak S, et al. Med Pr, 2016, 67(2):239
[49] Famele M, Palmisani J, Ferranti C, et al. J Sep Sci, 2017, 40(5):1049
[50] Aszyk J, Kubica P, Kotwasik A, et al. J Chromatogr A, 2017, 1519:45
[51] Shifflett J R, Watson L, McNally D J, et al. Chromatographia, 2018, 81:517
[52] Gu S Y, Li Y Q, Liu C Q, et al. Journal of Sichuan University (Medical Science Edition), 2008, 39(1):133 谷素英, 黎源倩, 刘驰青, 等. 四川大学学报(医学版), 2008, 39(1):133
[53] Yong L, Li Y Q, Xiao Q W, et al. Modern Preventive Medicine, 2009, 36(3):532 雍莉, 黎源倩, 肖全伟, 等. 现代预防医学, 2009, 36(3):532
[54] Li Can, Li Y Q. Modern Preventive Medicine, 2010, 37(2):315 李灿, 黎源倩. 现代预防医学, 2010, 37(2):315
[55] Han S L, Chen H, Liu T, et al. Journal of Analytical Science, 2015, 31(4):494 韩书磊, 陈欢, 刘彤, 等. 分析科学学报, 2015, 31(4):494
[56] Cai J L, Chen L, Peng B, et al. Acta Tabacaria Sinica, 2016, 22(5):1 蔡君兰, 陈黎, 彭斌, 等. 中国烟草学报, 2016, 22(5):1
[57] Yang S S, Smetena I, Huang C B. Anal Bioanal Chem, 2002, 373(8):839
[58] Xu Y J, Bai C M, Zhong K J, et al. Chinese Journal of Analytical Chemistry, 2006, 34(3):382 许燕娟, 白长敏, 钟科军, 等. 分析化学, 2006, 34(3):382
[59] Hossain A M, Salehuddin S M. Arab J Chem, 2013, 6(3):275
[60] Pagano T, Difrancesco A G, Smith S B, et al. Nicotine Tob Res, 2016, 18(5):700
[61] Ma L C, Xiao X M, Li D K, et al. Chinese Journal of Analysis Laboratory, 2016, 35(2):228 马立超, 肖晓明, 李登科, 等. 分析试验室, 2016, 35(2):228
[62] Shi J L, Pang T, Li Y, et al. Journal of Instrumental Analysis, 2014, 33(3):334 师君丽, 逄涛, 李勇, 等. 分析测试学报, 2014, 33(3):334
[63] Davoli E, Stramare L, Fanelli R, et al. J Chromatogr B Biomed Sci Appl, 1998, 707(1/2):312
[64] Ding M, Kobayashi Y T, Fukushima S J. Journal of Southwest University (Natural Science), 2007, 29(11):75 丁敏, 小林裕太, 福岛正充. 西南大学学报(自然科学版), 2007, 29(11):75
[65] Wang J L, Li G, Zhu Y, et al. Physical Testing and Chemical Analysis Part B:Chemical Analysis, 2015, 51(7):1003 王嘉乐, 李钢, 朱云, 等. 理化检验-化学分册, 2015, 51(7):1003
[66] Lozano A, Martínezuroz M A, Gómezramos M J, et al. Anal Bioanal Chem, 2012, 402(2):935
[67] Dobrowska J S, Erarpat S, Chormey D S, et al. J AOAC Int, 2016, 99(3):806
[68] Moldoveanu S C, Scott W A, Lawson D M. Beiträge Zur Tabakforschung International/Contributions to Tobacco Research, 2016, 27(2):54
[69] Ramírez N, Vallecillos L, Lewis A C, et al. J Chromatogr A, 2015, 1426:191
[70] Jorgenson J W, Lukacs K D. Anal Chem, 1981, 53:1298
[71] Huang L F, He M, Chen B B, et al. Chinese Journal of Chromatography, 2014, 32(10):1066 黄林芳, 何蔓, 陈贝贝, 等. 色谱, 2014, 32(10):1066
[72] Soto V C, Jofré V P, Galmarini C R, et al. Electrophoresis, 2016, 37(13):1909
[73] Marsh A, Clark B J. Electrophoresis, 2004, 25(9):1270
[74] Zhao L M, Chen X M, Tian X T, et al. Chinese Journal of Analytical Chemistry, 2013, 41(8):1274 赵利敏, 陈晓梅, 田晓田, 等. 分析化学, 2013, 41(8):1274
[75] Lochmann H, Bazzanella A, Kropsch S, et al. J Chromatogr A, 2001, 917(1/2):311
[76] Yang C Y, Chang M H, Chen S M, et al. Int J Electrochem Sc, 2016, 11(4):2650
[77] Jing Y Q, Lin E, Su X H, et al. RSC Adv, 2016, 6(31):26247
[78] Jing Y, Yuan X X, Yuan Q, et al. Sci Rep, 2016, 6:1
[79] Izadkhah V, Mortazavi S S, Farmany A. Particul Sci Technol, 2016, 34(5):552
[80] Shehata M, Azab S M, Fekry A M, et al. Biosens Bioelectron, 2016, 79:589