关键词: 功能材料, 蛋白质组学, 固定化酶, 蛋白质翻译后修饰, 转录因子, ¹⁸O标记, 综述

Abstract: With the increasing depth of proteomic identification, quantitative accuracy and increasing analytical speed, new challenges are being encountered in the development of proteomics methods. Traditional proteomics methods are time-consuming and have low sensitivity and poor accuracy; hence, they do not satisfy the new demands in proteomics research. Preparation of novel materials with specific functions via chemical and biochemical routes or by methods based on electricity, magnetism, heat, and photoirradiation is the key to overcome the limitations of traditional analytical techniques and promote active research in the field of proteomics. This paper reviews the recent advances in the application of functional materials in proteomics researches.

Key words: functional materials, proteomics, immobilized enzyme, protein post-translational modification, transcription factor, ¹⁸O labelling, review