色谱 ›› 2023, Vol. 41 ›› Issue (1): 76-86.DOI: 10.3724/SP.J.1123.2022.03043
徐敦明1, 吴易峰1, 王一帆1, 陈芳芳2,*(), 张书迪2, 赖国银3
收稿日期:
2022-04-06
出版日期:
2023-01-08
发布日期:
2023-01-12
通讯作者:
陈芳芳
基金资助:
XU Dunming1, WU Yifeng1, WANG Yifan1, CHEN Fangfang2,*(), ZHANG Shudi2, LAI Guoyin3
Received:
2022-04-06
Online:
2023-01-08
Published:
2023-01-12
Contact:
CHEN Fangfang
Supported by:
摘要:
随着化妆品种类的日益增多,化妆品中的香精香料成分受到了越来越多人的关注,建立化妆品中香精香料成分的分析测定方法是消除人们担忧最有效的措施之一。该研究建立了气相色谱-串联质谱(GC-MS/MS)同时测定化妆品中28种香料残留的方法。样品由甲醇提取,含油脂较多的经中性氧化铝固相萃取小柱净化,色素多、基质复杂的由QuEChERS净化,待测物采用GC-MS/MS测定,以保留时间和特征离子对定性,外标法定量。实验结果表明,分析物质的检出限(S/N=3)为2~20 μg/kg,定量限(S/N>10)为5~50 μg/kg。28种物质分别在1~100、2~200、4~200、10~1000 μg/L范围内线性关系良好,分析物质的线性相关系数(r2)>0.999。在空白样品中添加28种香料,添加水平为50~500 μg/kg时,回收率范围为71.3%~120.4%, RSD范围为1.5%~14.6%。该方法可对28种香料成分进行准确测定,不但可以有效排除复杂基体的干扰,而且简单、灵敏、稳定,能够很好地应用于化妆品中香料的含量测定。通过该方法对16种化妆品中的香精香料成分进行测定,发现12种化妆品中均检出相关香料成分,说明化妆品中的香精香料安全应引起重视。
中图分类号:
徐敦明, 吴易峰, 王一帆, 陈芳芳, 张书迪, 赖国银. 气相色谱-串联质谱法同时测定化妆品中28种香料成分[J]. 色谱, 2023, 41(1): 76-86.
XU Dunming, WU Yifeng, WANG Yifan, CHEN Fangfang, ZHANG Shudi, LAI Guoyin. Simultaneous determination of 28 fragrance components in cosmetics by gas chromatography-tandem mass spectrometry[J]. Chinese Journal of Chromatography, 2023, 41(1): 76-86.
No. | Compound | CAS No. | Retention time/min | Product ions (m/z) | Collision energy/eV |
---|---|---|---|---|---|
1 | limonene (柠檬烯) | 5989-27-5 | 5.28 | 93.00/91.10 | 12 |
93.00/51.10 | 9 | ||||
93.00/77.00* | 27 | ||||
2 | benzyl alcohol (苯甲醇) | 100-51-6 | 5.28 | 79.00/51.00 | 15 |
108.00/93.30 | 21 | ||||
79.00/77.10* | 6 | ||||
3 | linalool (芳樟醇) | 78-70-6 | 7.20 | 93.00/77.10 | 6 |
69.00/41.10 | 9 | ||||
71.00/43.00* | 9 | ||||
4 | methyl α-octynoate (α-辛炔酸甲酯) | 111-12-6 | 9.48 | 79.00/77.00 | 3 |
123.00/77.00 | 18 | ||||
123.00/67.00* | 9 | ||||
5 | citronellol (香茅醇) | 106-22-9 | 9.98 | 123.00/81.10 | 6 |
81.00/41.10 | 3 | ||||
69.00/41.00* | 15 | ||||
6 | geraniol (香叶醇) | 106-24-1 | 10.46 | 93.00/77.00 | 12 |
69.00/67.10 | 12 | ||||
69.00/41.00* | 3 | ||||
7 | citral (柠檬醛) | 5392-40-5 | 10.76 | 69.00/39.00 | 6 |
137.00/109.00 | 24 | ||||
69.00/41.10* | 6 | ||||
8 | cinnamaldehyde (肉桂醛) | 104-55-2 | 10.88 | 131.00/103.00 | 12 |
77.00/51.00 | 9 | ||||
103.00/77.10* | 9 | ||||
9 | hydroxycitronellal (羟基香茅醛) | 107-75-5 | 11.04 | 81.00/79.10 | 6 |
96.00/79.10 | 9 | ||||
96.00/81.10* | 15 | ||||
10 | anise alcohol (茴香醇) | 105-13-5 | 11.08 | 138.00/121.00 | 18 |
138.00/77.00 | 21 | ||||
109.00/77.00* | 36 | ||||
11 | cinnamyl alcohol (肉桂醇) | 104-54-1 | 11.44 | 92.00/65.10 | 6 |
134.00/90.80 | 24 | ||||
134.00/92.00* | 24 | ||||
12 | eugenol (丁香酚) | 97-53-0 | 12.16 | 164.00/149.00 | 18 |
164.00/90.40 | 12 | ||||
164.00/54.50* | 18 | ||||
13 | methyl eugenol (甲基丁香酚) | 93-15-2 | 12.84 | 147.00/91.20 | 6 |
178.00/107.20 | 9 | ||||
178.00/147.10* | 15 | ||||
14 | coumarin (香豆素) | 91-64-5 | 13.44 | 118.00/89.90 | 15 |
146.00/88.80 | 12 | ||||
146.00/118.20* | 33 | ||||
15 | isoeugenol (异丁香酚) | 97-54-1 | 13.56 | 164.00/77.20 | 9 |
164.00/132.10 | 36 | ||||
77.00/50.90* | 12 | ||||
16 | α-ionone (紫罗兰酮) | 127-41-3 | 13.92 | 135.00/78.90 | 15 |
135.00/91.10 | 9 | ||||
107.00/91.00* | 18 | ||||
17 | methyl isoeugenol (异丁香酚甲醚) | 93-16-3 | 14.16 | 178.00/107.10 | 9 |
107.00/79.00 | 9 | ||||
178.00/163.10* | 9 | ||||
18 | eugenol acetate (乙酸丁香酚酯) | 93-28-7 | 14.40 | 164.00/55.10 | 6 |
164.00/132.10 | 18 | ||||
164.00/149.10* | 6 | ||||
No. | Compound | CAS No. | Retention time/min | Product ions (m/z) | Collision energy/eV |
19 | butylphenyl methylpropional (铃兰醛) | 80-54-6 | 14.61 | 189.00/91.00 | 9 |
147.00/117.20 | 18 | ||||
189.00/131.00* | 21 | ||||
20 | acetyl isoeugenol (乙酰基异丁香酚) | 93-29-8 | 15.56 | 164.00/77.00 | 24 |
164.00/149.20 | 24 | ||||
164.00/103.00* | 15 | ||||
21 | amyl cinnamate (肉桂酸戊酯) | 3487-99-8 | 16.08 | 91.00/41.00 | 27 |
91.00/65.00 | 9 | ||||
115.00/63.00* | 9 | ||||
22 | lyral (新铃兰醛) | 31906-04-4 | 16.22 | 105.00/77.00 | 6 |
79.00/77.00 | 30 | ||||
107.00/79.20* | 12 | ||||
23 | α-amylcinnamyl alcohol (戊基肉桂醇) | 101-85-9 | 16.51 | 91.00/65.00 | 3 |
133.00/115.00 | 3 | ||||
133.00/55.00* | 15 | ||||
24 | farnesol (金合欢醇) | 4602-84-0 | 16.84 | 81.00/41.00 | 6 |
67.00/41.00 | 12 | ||||
69.00/41.10* | 12 | ||||
25 | hexyl cinnamal (α-己基肉桂醛) | 101-86-0 | 17.22 | 129.00/87.00 | 21 |
115.00/65.00 | 15 | ||||
115.00/89.00* | 21 | ||||
26 | benzyl benzoate (苯甲酸苄酯) | 120-51-4 | 17.49 | 77.00/51.10 | 15 |
91.00/65.10 | 12 | ||||
105.00/77.10* | 9 | ||||
27 | benzyl salicylate (水杨酸苄酯) | 118-58-1 | 18.61 | 91.00/39.10 | 15 |
91.00/41.10 | 24 | ||||
91.00/65.10* | 21 | ||||
28 | benzyl cinnamate (肉桂酸苄酯) | 103-41-3 | 20.83 | 91.00/65.00 | 12 |
131.00/77.10 | 12 | ||||
131.00/103.10* | 27 |
表1 28种香料成分的质谱检测参数
Table 1 MS parameters of the 28 fragrance components
No. | Compound | CAS No. | Retention time/min | Product ions (m/z) | Collision energy/eV |
---|---|---|---|---|---|
1 | limonene (柠檬烯) | 5989-27-5 | 5.28 | 93.00/91.10 | 12 |
93.00/51.10 | 9 | ||||
93.00/77.00* | 27 | ||||
2 | benzyl alcohol (苯甲醇) | 100-51-6 | 5.28 | 79.00/51.00 | 15 |
108.00/93.30 | 21 | ||||
79.00/77.10* | 6 | ||||
3 | linalool (芳樟醇) | 78-70-6 | 7.20 | 93.00/77.10 | 6 |
69.00/41.10 | 9 | ||||
71.00/43.00* | 9 | ||||
4 | methyl α-octynoate (α-辛炔酸甲酯) | 111-12-6 | 9.48 | 79.00/77.00 | 3 |
123.00/77.00 | 18 | ||||
123.00/67.00* | 9 | ||||
5 | citronellol (香茅醇) | 106-22-9 | 9.98 | 123.00/81.10 | 6 |
81.00/41.10 | 3 | ||||
69.00/41.00* | 15 | ||||
6 | geraniol (香叶醇) | 106-24-1 | 10.46 | 93.00/77.00 | 12 |
69.00/67.10 | 12 | ||||
69.00/41.00* | 3 | ||||
7 | citral (柠檬醛) | 5392-40-5 | 10.76 | 69.00/39.00 | 6 |
137.00/109.00 | 24 | ||||
69.00/41.10* | 6 | ||||
8 | cinnamaldehyde (肉桂醛) | 104-55-2 | 10.88 | 131.00/103.00 | 12 |
77.00/51.00 | 9 | ||||
103.00/77.10* | 9 | ||||
9 | hydroxycitronellal (羟基香茅醛) | 107-75-5 | 11.04 | 81.00/79.10 | 6 |
96.00/79.10 | 9 | ||||
96.00/81.10* | 15 | ||||
10 | anise alcohol (茴香醇) | 105-13-5 | 11.08 | 138.00/121.00 | 18 |
138.00/77.00 | 21 | ||||
109.00/77.00* | 36 | ||||
11 | cinnamyl alcohol (肉桂醇) | 104-54-1 | 11.44 | 92.00/65.10 | 6 |
134.00/90.80 | 24 | ||||
134.00/92.00* | 24 | ||||
12 | eugenol (丁香酚) | 97-53-0 | 12.16 | 164.00/149.00 | 18 |
164.00/90.40 | 12 | ||||
164.00/54.50* | 18 | ||||
13 | methyl eugenol (甲基丁香酚) | 93-15-2 | 12.84 | 147.00/91.20 | 6 |
178.00/107.20 | 9 | ||||
178.00/147.10* | 15 | ||||
14 | coumarin (香豆素) | 91-64-5 | 13.44 | 118.00/89.90 | 15 |
146.00/88.80 | 12 | ||||
146.00/118.20* | 33 | ||||
15 | isoeugenol (异丁香酚) | 97-54-1 | 13.56 | 164.00/77.20 | 9 |
164.00/132.10 | 36 | ||||
77.00/50.90* | 12 | ||||
16 | α-ionone (紫罗兰酮) | 127-41-3 | 13.92 | 135.00/78.90 | 15 |
135.00/91.10 | 9 | ||||
107.00/91.00* | 18 | ||||
17 | methyl isoeugenol (异丁香酚甲醚) | 93-16-3 | 14.16 | 178.00/107.10 | 9 |
107.00/79.00 | 9 | ||||
178.00/163.10* | 9 | ||||
18 | eugenol acetate (乙酸丁香酚酯) | 93-28-7 | 14.40 | 164.00/55.10 | 6 |
164.00/132.10 | 18 | ||||
164.00/149.10* | 6 | ||||
No. | Compound | CAS No. | Retention time/min | Product ions (m/z) | Collision energy/eV |
19 | butylphenyl methylpropional (铃兰醛) | 80-54-6 | 14.61 | 189.00/91.00 | 9 |
147.00/117.20 | 18 | ||||
189.00/131.00* | 21 | ||||
20 | acetyl isoeugenol (乙酰基异丁香酚) | 93-29-8 | 15.56 | 164.00/77.00 | 24 |
164.00/149.20 | 24 | ||||
164.00/103.00* | 15 | ||||
21 | amyl cinnamate (肉桂酸戊酯) | 3487-99-8 | 16.08 | 91.00/41.00 | 27 |
91.00/65.00 | 9 | ||||
115.00/63.00* | 9 | ||||
22 | lyral (新铃兰醛) | 31906-04-4 | 16.22 | 105.00/77.00 | 6 |
79.00/77.00 | 30 | ||||
107.00/79.20* | 12 | ||||
23 | α-amylcinnamyl alcohol (戊基肉桂醇) | 101-85-9 | 16.51 | 91.00/65.00 | 3 |
133.00/115.00 | 3 | ||||
133.00/55.00* | 15 | ||||
24 | farnesol (金合欢醇) | 4602-84-0 | 16.84 | 81.00/41.00 | 6 |
67.00/41.00 | 12 | ||||
69.00/41.10* | 12 | ||||
25 | hexyl cinnamal (α-己基肉桂醛) | 101-86-0 | 17.22 | 129.00/87.00 | 21 |
115.00/65.00 | 15 | ||||
115.00/89.00* | 21 | ||||
26 | benzyl benzoate (苯甲酸苄酯) | 120-51-4 | 17.49 | 77.00/51.10 | 15 |
91.00/65.10 | 12 | ||||
105.00/77.10* | 9 | ||||
27 | benzyl salicylate (水杨酸苄酯) | 118-58-1 | 18.61 | 91.00/39.10 | 15 |
91.00/41.10 | 24 | ||||
91.00/65.10* | 21 | ||||
28 | benzyl cinnamate (肉桂酸苄酯) | 103-41-3 | 20.83 | 91.00/65.00 | 12 |
131.00/77.10 | 12 | ||||
131.00/103.10* | 27 |
图5 28种香料成分的总离子流图
Fig. 5 TICs of the 28 fragrance components 1. limonene; 2. benzyl alcohol; 3. linalool; 4. methyl α-octynoate; 5. citronellol; 6. geraniol; 7. citral; 8. cinnamaldehyde; 9. hydroxycitronellal; 10. anise alcohol; 11. cinnamyl alcohol; 12. eugenol; 13. methyleugenol; 14. coumarin; 15. isoeugenol; 16. α-ionone; 17. methyl isoeugenol; 18. eugenyl acetate; 19. butylphenyl methylpropional; 20. acetyl isoeugenol; 21. amyl cinnamate; 22. lyral; 23. α-amylcinnamyl alcohol; 24. farnesol; 25. hexyl cinnamal; 26. benzyl benzoate; 27. benzyl salicylate; 28. benzyl cinnamate.
No. | Compound | Linear equation | r2 | Linear range/(μg/L) | LOD/(μg/kg) | LOQ/(μg/kg) |
---|---|---|---|---|---|---|
1 | limonene | Y=9.02×107X+2.81×106 | 0.9991 | 1-100 | 2 | 5 |
2 | benzyl alcohol | Y=8.78×107X-3.86×105 | 0.9992 | 1-100 | 2 | 5 |
3 | linalool | Y=8.47×105X-1.39×103 | 0.9997 | 10-1000 | 20 | 50 |
4 | methyl α-octynoate | Y=8.41×105X-3.55×103 | 0.9993 | 10-1000 | 20 | 50 |
5 | citronellol | Y=1.40×106X-1.77×103 | 0.9991 | 4-200 | 7 | 20 |
6 | geraniol | Y=2.51×106X-7.87×105 | 0.9991 | 4-200 | 7 | 20 |
7 | citral | Y=2.85×106X+1.03×103 | 0.9990 | 4-200 | 7 | 20 |
8 | cinnamaldehyde | Y=3.34×106X-8.11×103 | 0.9992 | 2-200 | 3 | 10 |
9 | hydroxycitronellal | Y=1.01×106X+1.64×103 | 0.9997 | 10-1000 | 20 | 50 |
10 | anise alcohol | Y=5.89×106X-1.61×105 | 0.9991 | 1-100 | 2 | 5 |
11 | cinnamyl alcohol | Y=6.51×106X-4.98×103 | 0.9990 | 1-100 | 2 | 5 |
12 | eugenol | Y=4.53×105X-3.84×102 | 0.9994 | 10-1000 | 20 | 50 |
13 | methyl eugenol | Y=9.38×106X-2.65×104 | 0.9993 | 1-100 | 2 | 5 |
14 | coumarin | Y=2.34×106X-3.13×104 | 0.9991 | 4-200 | 7 | 20 |
15 | isoeugenol | Y=9.60×105X-3.11×103 | 0.9998 | 10-1000 | 20 | 50 |
16 | α-ionone | Y=1.31×106X+1.13×102 | 0.9999 | 4-200 | 7 | 20 |
17 | methyl isoeugenol | Y=1.44×106X-4.61×104 | 0.9991 | 4-200 | 7 | 20 |
18 | eugenol acetate | Y=1.01×106X+6.57×103 | 0.9991 | 4-200 | 7 | 20 |
19 | butylphenyl methylpropional | Y=4.85×105X-5.07×103 | 0.9991 | 10-1000 | 20 | 50 |
20 | acety isoeugenol | Y=4.61×105X+1.26×104 | 0.9990 | 10-1000 | 20 | 50 |
21 | amyl cinnamate | Y=2.37×106X+1.07×104 | 0.9993 | 2-200 | 3 | 10 |
22 | lyral | Y=1.05×106X+2.36×103 | 0.9997 | 4-200 | 7 | 20 |
23 | α-amylcinnamyl alcohol | Y=8.05×106X+1.24×106 | 0.9994 | 1-100 | 2 | 5 |
24 | farnesol | Y=6.11×105X+2.23×103 | 0.9999 | 10-1000 | 20 | 50 |
25 | hexyl cinnamal | Y=5.30×106X+9.80×102 | 0.9996 | 1-100 | 2 | 5 |
26 | benzyl benzoate | Y=4.73×106X-5.83×104 | 0.9991 | 1-100 | 2 | 5 |
27 | benzyl salicylate | Y=2.04×106X-7.22×102 | 0.9996 | 4-200 | 7 | 20 |
28 | benzyl cinnamate | Y=2.08×106X+3.98×104 | 0.9999 | 4-200 | 7 | 20 |
表2 28种香料成分的线性方程、相关系数、线性范围、检出限和定量限
Table 2 Linear equations, correlation coefficients (r2), linear ranges, LODs, and LOQs of the 28 fragrance components
No. | Compound | Linear equation | r2 | Linear range/(μg/L) | LOD/(μg/kg) | LOQ/(μg/kg) |
---|---|---|---|---|---|---|
1 | limonene | Y=9.02×107X+2.81×106 | 0.9991 | 1-100 | 2 | 5 |
2 | benzyl alcohol | Y=8.78×107X-3.86×105 | 0.9992 | 1-100 | 2 | 5 |
3 | linalool | Y=8.47×105X-1.39×103 | 0.9997 | 10-1000 | 20 | 50 |
4 | methyl α-octynoate | Y=8.41×105X-3.55×103 | 0.9993 | 10-1000 | 20 | 50 |
5 | citronellol | Y=1.40×106X-1.77×103 | 0.9991 | 4-200 | 7 | 20 |
6 | geraniol | Y=2.51×106X-7.87×105 | 0.9991 | 4-200 | 7 | 20 |
7 | citral | Y=2.85×106X+1.03×103 | 0.9990 | 4-200 | 7 | 20 |
8 | cinnamaldehyde | Y=3.34×106X-8.11×103 | 0.9992 | 2-200 | 3 | 10 |
9 | hydroxycitronellal | Y=1.01×106X+1.64×103 | 0.9997 | 10-1000 | 20 | 50 |
10 | anise alcohol | Y=5.89×106X-1.61×105 | 0.9991 | 1-100 | 2 | 5 |
11 | cinnamyl alcohol | Y=6.51×106X-4.98×103 | 0.9990 | 1-100 | 2 | 5 |
12 | eugenol | Y=4.53×105X-3.84×102 | 0.9994 | 10-1000 | 20 | 50 |
13 | methyl eugenol | Y=9.38×106X-2.65×104 | 0.9993 | 1-100 | 2 | 5 |
14 | coumarin | Y=2.34×106X-3.13×104 | 0.9991 | 4-200 | 7 | 20 |
15 | isoeugenol | Y=9.60×105X-3.11×103 | 0.9998 | 10-1000 | 20 | 50 |
16 | α-ionone | Y=1.31×106X+1.13×102 | 0.9999 | 4-200 | 7 | 20 |
17 | methyl isoeugenol | Y=1.44×106X-4.61×104 | 0.9991 | 4-200 | 7 | 20 |
18 | eugenol acetate | Y=1.01×106X+6.57×103 | 0.9991 | 4-200 | 7 | 20 |
19 | butylphenyl methylpropional | Y=4.85×105X-5.07×103 | 0.9991 | 10-1000 | 20 | 50 |
20 | acety isoeugenol | Y=4.61×105X+1.26×104 | 0.9990 | 10-1000 | 20 | 50 |
21 | amyl cinnamate | Y=2.37×106X+1.07×104 | 0.9993 | 2-200 | 3 | 10 |
22 | lyral | Y=1.05×106X+2.36×103 | 0.9997 | 4-200 | 7 | 20 |
23 | α-amylcinnamyl alcohol | Y=8.05×106X+1.24×106 | 0.9994 | 1-100 | 2 | 5 |
24 | farnesol | Y=6.11×105X+2.23×103 | 0.9999 | 10-1000 | 20 | 50 |
25 | hexyl cinnamal | Y=5.30×106X+9.80×102 | 0.9996 | 1-100 | 2 | 5 |
26 | benzyl benzoate | Y=4.73×106X-5.83×104 | 0.9991 | 1-100 | 2 | 5 |
27 | benzyl salicylate | Y=2.04×106X-7.22×102 | 0.9996 | 4-200 | 7 | 20 |
28 | benzyl cinnamate | Y=2.08×106X+3.98×104 | 0.9999 | 4-200 | 7 | 20 |
No. | Compound | Lipstick | Skin cream | Body lotion | |||||
---|---|---|---|---|---|---|---|---|---|
SPE | QuEChERS | SPE | QuEChERS | SPE | QuEChERS | ||||
1 | limonene | 80.4 | 82.7 | 87.6 | 89.6 | 91.3 | 93.2 | ||
2 | benzyl alcohol | 84.4 | 61.6 | 83.2 | 84.2 | 73.2 | 61.6 | ||
3 | linalool | 82.6 | 93.6 | 90.4 | 89.2 | 86.4 | 87.3 | ||
4 | methyl α-octynoate | 105.7 | 100.2 | 112.5 | 101.2 | 106.2 | 103.6 | ||
5 | citronellol | 92.1 | 90.3 | 91.6 | 80.2 | 90.3 | 92.4 | ||
6 | geraniol | 83.5 | 92.1 | 82.6 | 63.4 | 92.6 | 90.6 | ||
7 | citral | 86.1 | 84.3 | 84.9 | 65.6 | 77.4 | 87.6 | ||
8 | cinnamaldehyde | 96.5 | 94.6 | 91.2 | 89.6 | 90.6 | 92.1 | ||
9 | hydroxycitronellal | 87.2 | 96.2 | 102.3 | 84.5 | 101.2 | 102.3 | ||
10 | anise alcohol | 86.1 | 83.4 | 84.3 | 76.5 | 87.6 | 85.4 | ||
11 | cinnamyl alcohol | 72.2 | 62.3 | 87.2 | 84.6 | 87.4 | 76.2 | ||
12 | eugenol | 89.1 | 92.4 | 74.6 | 95.6 | 90.9 | 92.6 | ||
13 | methyleugenol | 103.5 | 66.2 | 103.6 | 102.6 | 99.4 | 80.2 | ||
14 | coumarin | 107.4 | 95.6 | 105.2 | 112.3 | 102.6 | 106.2 | ||
15 | isoeugenol | 106.4 | 102.2 | 88.9 | 100.6 | 83.5 | 101.2 | ||
16 | α-ionone | 97.2 | 114.6 | 112.3 | 111.2 | 106.4 | 106.9 | ||
17 | methyl isoeugenol | 104.3 | 102.2 | 101.3 | 103.6 | 98.9 | 87.2 | ||
18 | eugenol acetate | 111.2 | 84.2 | 112.3 | 103.2 | 101.2 | 83.2 | ||
19 | butylphenyl methylpropional | 106.3 | 109.2 | 101.6 | 102.6 | 98.2 | 79.4 | ||
20 | acety isoeugenol | 91.5 | 89.6 | 94.3 | 92.6 | 83.4 | 93.6 | ||
21 | amyl cinnamate | 98.4 | 98.4 | 95.6 | 98.4 | 92.6 | 92.8 | ||
22 | lyral | 114.3 | 106.8 | 109.6 | 106.4 | 106.2 | 63.6 | ||
23 | α-amylcinnamyl alcohol | 93.2 | 90.3 | 75.2 | 94.6 | 90.6 | 92.4 | ||
24 | farnesol | 76.8 | 79.6 | 87.2 | 86.4 | 76.9 | 97.9 | ||
25 | hexyl cinnamal | 94.6 | 93.2 | 78.4 | 90.2 | 80.6 | 92.6 | ||
26 | benzyl benzoate | 79.9 | 61.2 | 82.3 | 86.2 | 85.6 | 82.3 | ||
27 | benzyl salicylate | 73.6 | 84.6 | 80.4 | 80.3 | 82.6 | 71.1 | ||
28 | benzyl cinnamate | 72.4 | 85.6 | 81.2 | 93.1 | 78.6 | 76.7 |
表4 SPE和QuEChERS两种前处理方式下目标物的回收率(n=3)
Table 4 Recoveries of the target compounds using two pretreatment methods: SPE and QuEChERS (n=3) %
No. | Compound | Lipstick | Skin cream | Body lotion | |||||
---|---|---|---|---|---|---|---|---|---|
SPE | QuEChERS | SPE | QuEChERS | SPE | QuEChERS | ||||
1 | limonene | 80.4 | 82.7 | 87.6 | 89.6 | 91.3 | 93.2 | ||
2 | benzyl alcohol | 84.4 | 61.6 | 83.2 | 84.2 | 73.2 | 61.6 | ||
3 | linalool | 82.6 | 93.6 | 90.4 | 89.2 | 86.4 | 87.3 | ||
4 | methyl α-octynoate | 105.7 | 100.2 | 112.5 | 101.2 | 106.2 | 103.6 | ||
5 | citronellol | 92.1 | 90.3 | 91.6 | 80.2 | 90.3 | 92.4 | ||
6 | geraniol | 83.5 | 92.1 | 82.6 | 63.4 | 92.6 | 90.6 | ||
7 | citral | 86.1 | 84.3 | 84.9 | 65.6 | 77.4 | 87.6 | ||
8 | cinnamaldehyde | 96.5 | 94.6 | 91.2 | 89.6 | 90.6 | 92.1 | ||
9 | hydroxycitronellal | 87.2 | 96.2 | 102.3 | 84.5 | 101.2 | 102.3 | ||
10 | anise alcohol | 86.1 | 83.4 | 84.3 | 76.5 | 87.6 | 85.4 | ||
11 | cinnamyl alcohol | 72.2 | 62.3 | 87.2 | 84.6 | 87.4 | 76.2 | ||
12 | eugenol | 89.1 | 92.4 | 74.6 | 95.6 | 90.9 | 92.6 | ||
13 | methyleugenol | 103.5 | 66.2 | 103.6 | 102.6 | 99.4 | 80.2 | ||
14 | coumarin | 107.4 | 95.6 | 105.2 | 112.3 | 102.6 | 106.2 | ||
15 | isoeugenol | 106.4 | 102.2 | 88.9 | 100.6 | 83.5 | 101.2 | ||
16 | α-ionone | 97.2 | 114.6 | 112.3 | 111.2 | 106.4 | 106.9 | ||
17 | methyl isoeugenol | 104.3 | 102.2 | 101.3 | 103.6 | 98.9 | 87.2 | ||
18 | eugenol acetate | 111.2 | 84.2 | 112.3 | 103.2 | 101.2 | 83.2 | ||
19 | butylphenyl methylpropional | 106.3 | 109.2 | 101.6 | 102.6 | 98.2 | 79.4 | ||
20 | acety isoeugenol | 91.5 | 89.6 | 94.3 | 92.6 | 83.4 | 93.6 | ||
21 | amyl cinnamate | 98.4 | 98.4 | 95.6 | 98.4 | 92.6 | 92.8 | ||
22 | lyral | 114.3 | 106.8 | 109.6 | 106.4 | 106.2 | 63.6 | ||
23 | α-amylcinnamyl alcohol | 93.2 | 90.3 | 75.2 | 94.6 | 90.6 | 92.4 | ||
24 | farnesol | 76.8 | 79.6 | 87.2 | 86.4 | 76.9 | 97.9 | ||
25 | hexyl cinnamal | 94.6 | 93.2 | 78.4 | 90.2 | 80.6 | 92.6 | ||
26 | benzyl benzoate | 79.9 | 61.2 | 82.3 | 86.2 | 85.6 | 82.3 | ||
27 | benzyl salicylate | 73.6 | 84.6 | 80.4 | 80.3 | 82.6 | 71.1 | ||
28 | benzyl cinnamate | 72.4 | 85.6 | 81.2 | 93.1 | 78.6 | 76.7 |
Cosmetic type | Compounds |
---|---|
Toning lotion | limonene, benzyl alcohol |
Hair mask | benzyl alcohol, coumarin, benzyl benzoate |
Talcum powder | benzyl alcohol, linalool, geraniol, anise alcohol, cinnamyl alcohol, eugenol, coumarin, α-ionone, methyl isoeugenol, eugenol acetate, benzyl benzoate, benzyl salicylate |
Eye shadow | coumarin, α-ionone |
Moisturizing lotion | coumarin, α-ionone, butylphenyl methylpropional, benzyl salicylate |
Massage oil | coumarin, benzyl benzoate |
Lip gloss | coumarin, benzyl salicylate |
Skin cream | coumarin |
Shampoo | coumarin, farnesol, benzyl benzoate |
Body lotion | limonene, linalool, anise alcohol, cinnamyl alcohol, eugenol, methyl eugenol, coumarin, isoeugenol, α-ionone, methyl isoeugenol, eugenol acetate, lyral, farnesol, benzyl benzoate, benzyl salicylate, benzyl cinnamate |
Bath salt crystals | linalool, citronellol, citral, α-ionone, farnesol, benzyl benzoate, benzyl salicylate |
Lip balm | limonene, benzyl alcohol, linalool |
表5 部分化妆品中检出的香料成分
Table 5 Fragrance components detected in several cosmetics
Cosmetic type | Compounds |
---|---|
Toning lotion | limonene, benzyl alcohol |
Hair mask | benzyl alcohol, coumarin, benzyl benzoate |
Talcum powder | benzyl alcohol, linalool, geraniol, anise alcohol, cinnamyl alcohol, eugenol, coumarin, α-ionone, methyl isoeugenol, eugenol acetate, benzyl benzoate, benzyl salicylate |
Eye shadow | coumarin, α-ionone |
Moisturizing lotion | coumarin, α-ionone, butylphenyl methylpropional, benzyl salicylate |
Massage oil | coumarin, benzyl benzoate |
Lip gloss | coumarin, benzyl salicylate |
Skin cream | coumarin |
Shampoo | coumarin, farnesol, benzyl benzoate |
Body lotion | limonene, linalool, anise alcohol, cinnamyl alcohol, eugenol, methyl eugenol, coumarin, isoeugenol, α-ionone, methyl isoeugenol, eugenol acetate, lyral, farnesol, benzyl benzoate, benzyl salicylate, benzyl cinnamate |
Bath salt crystals | linalool, citronellol, citral, α-ionone, farnesol, benzyl benzoate, benzyl salicylate |
Lip balm | limonene, benzyl alcohol, linalool |
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