高分辨分离分析新技术在食品安全检测领域的应用进展

doi:10.3724/SP.J.1123.2023.08026

色谱 ›› 2023, Vol. 41 ›› Issue (11): 952-959.DOI: 10.3724/SP.J.1123.2023.08026

高分辨分离分析新技术在食品安全检测领域的应用进展

孙燕¹^,², 谢昀¹, 许秀丽¹, 谭明乾², 张峰¹^,²^,^*()

1.中国检验检疫科学研究院, 北京 100176
2.大连工业大学食品学院, 辽宁大连 116034

收稿日期:2023-08-31 出版日期:2023-11-08 发布日期:2023-11-16
基金资助:
国家市场监督管理总局科技创新人才计划(青年拔尖人才)(QNBJ202322)

Application progress of innovative high resolution separation and analysis technology in food safety detection field

SUN Yan¹^,², XIE Yun¹, XU Xiuli¹, TAN Mingqian², ZHANG Feng¹^,²^,^*()

1. Chinese Academy of Inspection and Quarantine, Beijing 100176, China
2. School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China

Received:2023-08-31 Online:2023-11-08 Published:2023-11-16
Contact: *Tel:(010)53897010,E-mail:fengzhang@126.com.
Supported by:
Innovation Talent Program of State Administration for Market Regulation(QNBJ202322)

摘要/Abstract

摘要：

近十年来,质谱技术在食品检验学中得到了广泛应用,同时仪器的不断改进是分析化学技术取得突破的关键。本文讨论了高分辨分离分析技术在食品安全检测领域的最新进展与应用(2013-2023年);重点介绍了在线质谱耦合技术、高分辨筛查技术以及微型质谱仪等创新发展技术;最后对食品安全检测新装置的开发进行了展望。

关键词: 在线质谱耦合技术, 高分辨筛查技术, 微型质谱仪, 食品安全

Abstract:

In the last decade, mass spectrometry (MS) has been widely used in food inspection science, and the continuous improvement of instruments is the key to the breakthrough of analytical chemistry technology. This paper discusses the latest progress and application of high resolution separation and analysis technology in food safety field (2013-2023), focusing on the innovative development technologies such as on-line MS coupling technology, high resolution screening technology and micro mass spectrometer. Finally, the development of new device in the field of food safety detection is prospected.

Key words: on-line mass spectrometry coupling technology, high resolution screening technology, micro mass spectrometer, food safety

中图分类号:

O658

孙燕, 谢昀, 许秀丽, 谭明乾, 张峰. 高分辨分离分析新技术在食品安全检测领域的应用进展[J]. 色谱, 2023, 41(11): 952-959.

SUN Yan, XIE Yun, XU Xiuli, TAN Mingqian, ZHANG Feng. Application progress of innovative high resolution separation and analysis technology in food safety detection field[J]. Chinese Journal of Chromatography, 2023, 41(11): 952-959.

图/表 3

图1 基于AI-Q-Orbitrap高碰撞解离的去质子化柠檬酸的3种裂解途径[22]

Fig. 1 Three proposed mentation pathway schemes for exemplified deprotonated citramalic acid by high collision dissociation of ambient ionization quadrupole-orbitrap (AI-Q-Orbitrap)[22]

图2 质谱特征列表优化器用于生成和处理非靶向LC-MS代谢组学数据库的工作流程[23]

Fig. 2 Mass spectral feature list optimizer (MS-FLO) workflow for the generation and processing of untargeted LC-MS-based metabolomics data[23]

图3 质谱树的3种预测方法示意图[25]

Fig. 3 Overview of three approaches to MS tree prediction[25] A. fragmentation prediction approaches; B. binned prediction approaches; C. formula prediction approaches.

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高分辨分离分析新技术在食品安全检测领域的应用进展

Application progress of innovative high resolution separation and analysis technology in food safety detection field

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