Development of intelligent monolithic stationary phase for chromatography

doi:10.3724/SP.J.1123.2013.03001

Abstract

Abstract:

In recent years, great attention has been paid to monolith, which is developed as a new generation of chromatographic stationary phase, due to its advantages of in-situ preparation, fast mass transfer and high permeability. Besides, as a class of functional materials, intelligent polymer could response to external environmental stimuli, such as temperature, pH, salt and so on. This intelligent polymer is usually modified onto solid support surface for fabrication of environmental responsive materials, which could be widely applied in drug release, chemical sensing, cell growth, etc. As a result, the construction of intelligent surface on monolith can provide new opportunities for its development in chromatography. This review summarizes the development of intelligent monolith as chromatographic stationary phase during recent years.

Key words: chromatographic stationary phase, development, intelligent polymer, monolith

CLC Number:

O658

SHEN Ying^,, QI Li^*, MAO Lanqun, CHEN Yi. Development of intelligent monolithic stationary phase for chromatography[J]. Chinese Journal of Chromatography, 2013, 31(4): 290-296.

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