Chinese Journal of Chromatography ›› 2013, Vol. 31 ›› Issue (4): 317-321.DOI: 10.3724/SP.J.1123.2012.10041

• Special column of chromatographic stationary phases • Previous Articles     Next Articles

Preparation of a novel polymer monolith using atom transfer radical polymerization method for solid phase extraction

SHEN Ying1,2, QI Li1*, QIAO Juan1, MAO Lanqun1, CHEN Yi1   

  1. 1. CAS Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China;2. University of Chinese Academy of Sciences, Beijing 100049, China
  • Received:2012-11-12 Online:2013-04-22 Published:2013-04-24

Abstract:

In this study, a novel polymer monolith based solid phase extraction (SPE) material has been prepared by two-step atom transfer radical polymerization (ATRP) method. Firstly, employing ethylene glycol dimethacrylate (EDMA) as a cross-linker, a polymer monolith filled in a filter head has been in-situ prepared quickly under mild conditions. Then, the activators generated by electron transfer ATRP (ARGET ATRP) was used for the modification of poly(2-(dimethylamino)ethyl-methacrylate) (PDMAEMA) on the monolithic surface. Finally, this synthesized monolith for SPE was successfully applied in the extraction and enrichment of steroids. The results revealed that ATRP can be developed as a facile and effective method with mild reaction conditions for monolith construction and has the potential for preparing monolith in diverse devices.

Key words: atom transfer radical polymerization (ATRP), polymer monolith, solid phase extraction

CLC Number: