Chinese Journal of Chromatography ›› 2016, Vol. 34 ›› Issue (12): 1154-1160.DOI: 10.3724/SP.J.1123.2016.08041

• Reviews • Previous Articles     Next Articles

Recent advances in single cell analysis technologies

LIU Jia, LIU Zhen   

  1. School of Chemistry and Chemical Engineering of Nanjing University, State Key Laboratory of Analytical Chemistry for Life Science, Nanjing 210023, China
  • Received:2016-08-31 Online:2016-12-08 Published:2013-04-24
  • Supported by:

    National Science Fund for Distinguished Young Scholars (No. 21425520); Key Grant from the National Natural Science Foundation of China (No. 21627810).

Abstract:

Cells are the basic units of the structure and activities of living species, and single cell-based research is the foundation of life science researches. Because of the tiny volume of cells, complex microenvironment within cells and the low concentrations of their components, single cell analysis is still a challenging task in many aspects. In this review, we summarize and discuss the recent advances in single cell analysis technologies, and emphasize the characteristics and the state of the applications of different techniques.

Key words: capillary electrophoresis (CE), mass spectrometry (MS), microfluidic chip, review, single cell analysis

CLC Number: