Multi-column technologies in chromatographic analysis

doi:10.3724/SP.J.1123.2018.11023

Abstract

Abstract:

Multi-column chromatographic technologies provide high throughput and high resolution separations through parallel, serial or parallel-serial column combinations. In comparison with classical single-column based chromatography, multi-column chromatography well satisfied the need for separations of large batch samples and highly complex bio-samples, and therefore attracted extensive interests. In this review, we discussed the recent developments in multi-column chromatography and its applications in multidimensional separation, chip chromatography, capillary electrophoresis, stationary-phase screening, and serial column chromatography. We also discussed the limitations and future developments in multi-column chromatography.

Key words: chip separation, high-throughput, multi-column chromatography, multidimensional chromatography, parallel/serial columns, review

CLC Number:

O658

WANG Xiaofei, SUN Kaiyue, ZHANG Bo. Multi-column technologies in chromatographic analysis[J]. Chinese Journal of Chromatography, 2019, 37(2): 123-131.

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