基于镜像酶正交酶切的蛋白质复合物规模化精准分析新方法

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韩若楠¹^,²^,^#, 赵丽丽²^,³^,^#, 安雨馨²^,³, 梁振², 赵群²^,^*(

), 张丽华², 张玉奎¹^,²

Mirror cutting-assisted orthogonal digestion enabling large-scale and accurate protein complex characterization

HAN Ruonan¹^,²^,^#, ZHAO Lili²^,³^,^#, AN Yuxin²^,³, LIANG Zhen², ZHAO Qun²^,^*(

), ZHANG Lihua², ZHANG Yukui¹^,²

图1. 胰蛋白酶与LysargiNase酶解样品的交联位点在牛血清白蛋白晶体结构(PDB: 3V03)的映射

Fig. 1. Mapping of cross-linked sites obtained from trypsin and LysargiNase digestion on the bovine serum albumin crystal structure (PDB: 3V03)