基于镜像酶正交酶切的蛋白质复合物规模化精准分析新方法

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韩若楠¹^,²^,^#, 赵丽丽²^,³^,^#, 安雨馨²^,³, 梁振², 赵群²^,^*(

), 张丽华², 张玉奎¹^,²

Mirror cutting-assisted orthogonal digestion enabling large-scale and accurate protein complex characterization

HAN Ruonan¹^,²^,^#, ZHAO Lili²^,³^,^#, AN Yuxin²^,³, LIANG Zhen², ZHAO Qun²^,^*(

), ZHANG Lihua², ZHANG Yukui¹^,²

图6. 大肠杆菌样品中LysargiNase与胰蛋白酶酶切鉴定蛋白质复合物信息互补性

Fig. 6. Complementation of protein complex information identified by LysargiNase and trypsin digestion in Escherichia coli samples
a. complementary of protein-protein interactions; b. example of complementary of intra-cross-linked protein structure information.